Anti-inflammatory Effect and Total Flavonoid Content of The Ethanolic Seed Extracts of Three Umbelliferae Species

  • Sumalee Panthong Department of Applied Thai Traditional Medicine, Faculty of Medicine, Thammasat University, Pathum Thani 12120, Thailand
  • Arunporn Itharat Department of Applied Thai Traditional Medicine, Faculty of Medicine, Thammasat University, Pathum Thani 12120, Thailand
  • Sasikarn Aukkanibut Department of Applied Thai Traditional Medicine, Faculty of Medicine, Thammasat University, Pathum Thani 12120, Thailand
  • Thanaporn Intarawan Department of Applied Thai Traditional Medicine, Faculty of Medicine, Thammasat University, Pathum Thani 12120, Thailand
Keywords: Anti-inflammation, Umbelliferae, Anethum graveolens, Cuminum cyminum, Foeniculum vulgare

Abstract

The seeds of three plants in Umbelliferae, namely Anethum graveolens, Cuminum cyminum and Foeniculum vulgare are used as ingredients in Thai traditional medicine for treating inflammation. Additionally, they are macerated in alcohol and used as a Thai traditional drug. Although A. graveolensm, C. cyminum and F. vulgare are members of the same family, these plants consist in chemical constituent. There are no studies comparing their anti-inflammatory properties. Our objectives were to investigate and compare the anti-inflammatory activity and total flavonoid content of the ethanolic seed extracts of these three species. Results showed that F. vulgare extract had the highest activity in inhibiting nitric oxide, IL-6 production and the highest flavonoid content. The ethanolic extract of C. cyminum showed moderate anti-inflammatory activity while A. graveolens showed no inhibition of nitric oxide, TNF-gif.latex?\alpha and IL-6 production. F. vulgare extract had the best anti -inflammatory properties that were related to total flavonoid content and should be now be assessed in animal models.

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Published
2020-12-24
How to Cite
Panthong, S., Itharat, A., Aukkanibut, S., & Intarawan, T. (2020). Anti-inflammatory Effect and Total Flavonoid Content of The Ethanolic Seed Extracts of Three Umbelliferae Species. Science & Technology Asia, 25(4), 174-181. Retrieved from https://ph02.tci-thaijo.org/index.php/SciTechAsia/article/view/208653
Section
Biological sciences