Anti Diabetic Potential of Cashew Nut (Anacardium occidentale) Shoots and Leaves Extracts under Simulated In Vitro Digestion

  • Thanakorn Damsud Faculty of Science and Technology, Rajamangala University of Technology Srivijaya, Nakhon Si Thammarat 80110, Thailand
  • Thitiworrada Tedphum Faculty of Science and Technology, Rajamangala University of Technology Srivijaya, Nakhon Si Thammarat 80110, Thailand
  • Chadaporn Sukkrong Faculty of Science and Technology, Rajamangala University of Technology Srivijaya, Nakhon Si Thammarat 80110, Thailand
  • Mary Ann Lila Plants for Human Health Institute, North Carolina State University, North Carolina 28081, United States
Keywords: Anacardium occidentale, Polyphenolics, In vitro digestion, α-Glucosidase inhibitor

Abstract

Anacardium occidentale has long been used for diabetes therapy; however, its active components remain unknown. This study aimed to investigate the phytochemical contents, especially phenolics and flavonoids, along with gif.latex?\alpha- glucosidase inhibitory activity and bioaccessibility, of extracts from the shoots and leaves of A. occidentale. The methanolic extract from leaves showed higher total phenolics (98.21±0.35g GAE/100 g extract) and total flavonoids (89.53±0.65 g RE/100 g extract) than the shoots extract. Upon bioaccessibility testing, phenolics and flavonoids from the leaf extract were more bioaccessible than those from the shoot extract. The  gif.latex?\alpha-glucosidase inhibitory activity of A. occidentale was higher when predigested than it was after stimulated gastric digestion and pancreatic digestion. These results suggest that A. occidentale has the potential to be used for diabetes therapy and as a functional food component.

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Published
2021-06-25
How to Cite
Damsud, T., Tedphum, T., Sukkrong, C., & Lila, M. A. (2021). Anti Diabetic Potential of Cashew Nut (Anacardium occidentale) Shoots and Leaves Extracts under Simulated In Vitro Digestion. Science & Technology Asia, 26(2), 138-144. Retrieved from https://ph02.tci-thaijo.org/index.php/SciTechAsia/article/view/219996
Section
Biological sciences