Efficacy and Safety of Intrathecal Morphine in Foot and Ankle Surgery Patients; A Retrospective Study

Authors

  • Preeyaphan Arunakul Department of Anesthesia, Faculty of Medicine, Thammasat University, Pathum Thani 12120, Thailand
  • Thanachit Ruangprach Department of Anesthesia, Faculty of Medicine, Thammasat University, Pathum Thani 12120, Thailand
  • Prapasri Kulalert Department of Clinical Epidemiology, Faculty of Medicine, Thammasat University, Pathum Thani 12120, Thailand
  • Marut Arunakul Department of Orthopedics, Faculty of Medicine, Thammasat University, Pathum Thani 12120, Thailand

Keywords:

Foot and ankle surgery (FAAS), Intrathecal morphine, Postoperative pain

Abstract

Intrathecal morphine is an effective technique for pain control, easy to perform and simply available in all clinical settings. Studies have reported that 0.1 mg of intrathecal morphine was effective and safe in hip surgery and cesarean section. However, the efficacy of intrathecal morphine for foot and ankle surgery (FAAS) was still unknown. We aimed to evaluate the efficacy of 0.1 mg intrathecal morphine for postoperative pain control within the first 24 hours after FAAS. Data was collected from 136 patients. The numerical rating scales (NRS) taken within the first 24 hours post-operation, written in patients’ medical records, were assessed. Records of time to first rescue analgesic, total rescue analgesic consumption, supplemental or multimodal analgesics, as well as incidence of nausea and vomiting, pruritus, urinary retention, and respiratory depression requiring treatment were also reviewed. The average NRS were less than 3 at 0, 6, 12, and 24 hours after intrathecal morphine administration. The number of patients who needed rescue analgesics in the first 24 hours was 25 (18.4%). Thirty-three patients (24.26 %) had nausea and vomiting, 9 patients (6.62%) had pruritus, and 16 patients (11.8 %) had urinary retention. None of the patients had respiratory depression. Therefore, it was concluded that 0.1 mg of intrathecal morphine is effective for controlling postoperative pain in FAAS, though appropriate dosage should be further studied; there are still some dose-dependent complications to be considered.

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Published

2022-12-31

How to Cite

Arunakul, P. ., Ruangprach, T. ., Kulalert, P. ., & Arunakul, M. . (2022). Efficacy and Safety of Intrathecal Morphine in Foot and Ankle Surgery Patients; A Retrospective Study. Science & Technology Asia, 27(4), 20–26. Retrieved from https://ph02.tci-thaijo.org/index.php/SciTechAsia/article/view/247899

Issue

Section

Biological sciences