Validation of a Deep Learning-Based Automated Detection Algorithm for Mobile Chest Radiographs of Patients with SARSCoV- 2 Infection in a Field Hospital
Keywords:
Chest radiographs, COVID-19 pneumonia, Deep learning-based automatic detection (DLAD) algorithm, SARS-CoV2 infectionAbstract
Due to the rapid spread of SARS-CoV2 infection, many hospitals had an influx patients along with more chest radiographs requiring interpretation. The deep learning- based automatic detection ( DLAD) algorithm was applied to help physicians and radiologists in reading this overwhelming number of chest radiographs. The aim of this study was to validate the diagnostic performance in COVID- 19 pneumonia detection of the DLAD for mobile chest radiographs in patients with SARS- CoV- 2 infection. Chest radiographs of patients with RT-PCR confirmed SARS-CoV- 2 infection were included. The diagnostic performance of DLAD in the detection of COVID- 19 pneumonia with mobile chest radiographs was evaluated in comparison to the prior interpretation by the radiologist. The sensitivity and specificity of DLAD in identification of pneumonia were 27.6% (95%CI 22.3%-33.4%) and 99.8% (95%CI 98.6%-100%) respectively. PPV and NPV were 98.7% (95%CI 92.8%-100%) and 67.4% (95%CI 63.5%-71.2%) respectively, with an AUC of 0.64 (95%CI 0.61-0.66). The duration from the onset of symptoms to the time of chest radiography was a significant predictor of pneumonia (P=0.013) whereas sex, age, BMI, and symptoms were not. DLAD is a tool with excellent specificity and PPV for COVID-19 pneumonia detection but has low sensitivity and AUC.
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