Survival of Patients with Traumatic Brain Injury in Khon Kaen Hospital During 2008-2018
Keywords:
Traumatic Brain Injury (TBI), SurvivalAbstract
Traumatic brain injury (TBI) is one of the main causes of deaths for people around the world. The purpose of this study was to study the rate, time range, and the factors related to the survival time of traumatic brain injury patients. We performed a retrospective cohort study involving 10,584 patients with TBI who were registered in the Injury Surveillance (IS) of Khon Kaen Hospital during the years of 2008 to2018.Survival curves were estimated by the Kaplan-Meier method. Multivariable analysis were conducted by Cox’s proportional hazard regression model. Results were found the survival rate for 1, 3, and 5 months were found about 80.15%, 52.35% and 45.91% of the patients with TBI, respectively. The median survival time was 3.03 months (95%CI=1.35-4.72). The factors related to survival rate by Cox’s proportional hazard regression analysis were age of ≥ 61 years (HRadj =2.02, 95%CI=1.48-2.74), cause of falls (HRadj = 1.50, 95% CI = 1.14-1.97), the Revised Trauma Score as severe (RTS 0-4) (HRadj =5.47, 95%CI=4.10-7.29), and the Injury Severity Score (ISS) as severe (ISS 25-75) (HRadj =10.76, 95%CI=6.67-17.37). Suggestions; the comprehensive treatment system for traumatic brain injury should be increase developed such as prevention of falls in the elderly, wearing the helmet to reduce the severity of injury.
References
Centers for Disease Control and Prevention National Center for Injury Prevention and Control (CDC). Surveillance Report of Traumatic Brain Injury related Emergency Department Visits, Hospitalizations, and Deaths UNITED STATES [Internet]. 2014. [cited 2019 September 27]. Available from: https://www.cdc.gov/traumaticbraininjury/pdf/TBI-Surveillance-Report-FINAL_508.pdf
Boyd DR, Cowley RA. Comprehensive regional trauma/emergency medical services (EMS) delivery systems: the United States experience. World J Surg. 1983; 7:149–157
Hon-Yi Shi, Shiuh-Lin Hwang, King-Teh Lee, Chih-Lung Lin. Temporal trends and volume-outcome associations after traumatic brain injury: a 12-year study in Taiwan. Journal of Neurosurgery. 2013; 118(4): 732-738.
Bekelis K, Missios S, Mackenzie TA. Prehospital Helicopter Transport and Survival of Patients With Traumatic Brain Injury. Annals of Surgery. 2015; 261(3): 579-585.
Schoenfeld AD, Richter RJ. Nomograms for Calculating the Number of Patients Needed for a Clinical Trial with Survival as an Endpoint. Biometrics. 1982; 38:163-170.
Tohme S, Delhumeau C, Zuercher M, Haller G, Walder B. Prehospital risk factors of mortality and impaired consciousness after severe traumatic brain injury: an epidemiological study. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine. 2014; 22:1.
Brown AWLC, Malec JF, Perkins PK, Diehl NN, Larson DR. Long-term survival after traumatic brain injury: a population-based analysis. NeuroRehabilitation. 2004;19(1):37-43.
Tuma M, El-Menyar A, Abdelrahman H, Al-Thani H, Zarour A, Parchani A, et al., Prehospital Intubation in Patients with Isolated Severe Traumatic Brain Injury: A 4-Year Observational Study. Critical Care Research and Practice. 2014;2014:135986.
Harrison-Felix C K-HS, Hammond FM, Wang R, Englander J, Dams-O’Connor K, Kreider SE, Novack TA, Diaz-Arrastia R. Mortality after surviving traumatic brain injury: risks based on age groups. J Head Trauma Rehabil. 2012; 27(6):E45-56.
Haring RS, Narang K, Canner JK, Asemota AO, George BP, Selvarajah S, et al., Traumatic brain injury in the elderly: morbidity and mortality trends and risk factors. Journal of Surgical Research. 2015;195(1):1-9.
Utomo WK, Gabbe BJ, Simpson PM, Cameron PA. Predictors of in-hospital mortality and 6-month functional outcomes in older adults after moderate to severe traumatic brain injury. Injury. 2009; 40(9):973-977.
Peck KA CR, Sise CB, Johnson J, Yen JW, Sise MJ, Dunne CE, et al. Death after discharge: Predictors of mortality in older brain-injured patients. Journal of Trauma and Acute Care Surgery.2014; 77(6):978-983.
El-Matbouly M, El-Menyar A, Al-Thani H, Tuma M, El-Hennawy H, AbdulRahman H, et al. Traumatic Brain Injury in Qatar: Age Matters Insights from a 4-Year Observational Study. The Scientific World Journal 2013; 2013:354920.
