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Multimodal medical image fusion (MIF) is the procedure of integrating different images in single into multiple imaging modalities for increasing the image quality by preserving a certain feature. Medical image combination covered a tremendous count of hot topic areas, involving pattern recognition, image processing, artificial intelligence (AI), computer vision (CV), and machine learning (ML). In addition, MIF was more commonly applied in clinical for physicians to understand the lesion by the combination of various modalities of medicinal image. This article introduces a novel bacterial foraging optimization-based multimodal medical image fusion approach (BFO-M3IFA). The presented BFO-M3IFA technique considered two distinct patterns of the images as the input of systems and the outcome will be the fused image. Primarily, the BFO-M3IFA technique exploits Weiner filtering (WF) technique as an image pre-processing step to get rid of the noise. Besides, discrete wavelet transform (DWT) was applied for decomposing the image into distinct subbands. Afterward, the estimated coefficients of modality 1 and comprehensive coefficients of modality 2 are integrated and vice versa. At last, a fusion rule is generated to fuse the details of two image modalities and the optimal fusion rule parameter is chosen with utilize of BFO algorithm. The experimental validation of the BFO-M3IFA system was tested and outcomes ensured the improved performance of the BFO-M3IFA system on existing models.
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