Preparation of zinc oxide nanoparticles for cancer treatment
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Abstract
Zinc oxide nanoparticles (ZnO NPs) have become one of the most popular metal oxide nanoparticles due to their excellent biocompatibility, economic, and low toxicity. Various methods of synthesis have been adopted in the production of ZnO NPs to meet its high demand. The environmental implications and economic challenges attached to most of the means of ZnO NPs synthesis have resulted in the quest for other alternatives with environmental and economic benefits. Recently in nanotechnology research, synthesis of nanoparticle from green chemistry pathways has been preferred due to its natural biological reduction property which reduces the utilization and exposure of toxic chemical to the environment when compared to physical and chemical methods. ZnO NPs have emerged a promising potential in biomedicine, especially in the fields of anticancer and antibacterial fields, which are involved with their potent ability to trigger excess reactive oxygen species (ROS) production, release zinc ions, and induce cell apoptosis. In addition, zinc is well known to keep the structural integrity of insulin. So, ZnO NPs also have been effectively developed for cancer treatment.
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References
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