The Development of Heel’s Crack Healing Cream from the Seed Coat of Trichosanthes tricuspidata Lour.

Abstract

The purpose of this research was to develop heel’s crack healing cream from the seed coat of Trichosanthes tricuspidata Lour. extract. Freeze-Thaw cycling test was performed to investigate physical compatibility between active ingredients and other ingredients in the preparations. Heel’s crack healing efficiency was studied in volunteers comparing a cream base and a cream base with the seed coat of Trichosanthes tricuspidata Lour. extract for 4 weeks. The volunteers' satisfaction was also evaluated using questionnaires. All developed preparations showed physical stability when they were stored during a Freeze-Thaw cycling test. The results show that the healing of a cracked heel with a cream base with the seed coat of Trichosanthes tricuspidata Lour. extract is more effective than using a cream base. The results indicate that the volunteers are more satisfied with the cracked heal healing process from a combination of seed coat of Trichosanthes tricuspidata Lour. extract and cream base than they were with using only a cream base alone.