Serum and milk leptin concentrations in Thai native beef cows (Bos indicus) affect their offspring’s body weight
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Abstract
It has been proposed that maternal serum leptin provides a link between milk leptin and offspring growth and development. Moreover, it may play a role in regulating offspring appetite and food intake in early life. Serum leptin concentration has never been investigated in beef cows, and the link between milk leptin and offspring growth has never been studied. The aims were to investigate whether changes in serum and milk leptin concentrations during postpartum in Thai native beef cows (Bos indicus) affect their offspring’s body weight and serum leptin concentration. Cow blood and milk samples were collected during 42 days after calving. Calf blood samples were collected, and their body weight was also measured. Serum and milk leptin concentrations were determined using enzyme-linked immunosorbent assay (ELISA). In beef cows, serum and milk leptin concentrations were gradually decreased after postpartum. There was a strong positive correlation between serum and milk leptin (r2 = 0.73; P<0.01). Both serum and milk leptin concentrations had a strong negative correlation with calf body weight (r2 = -0.71; P<0.01 and r2 = -0.76; P<0.01, respectively). Interestingly, there were no correlations noted between calf serum leptin and calf body weight (r2 = -0.24), between calf serum leptin and cow serum leptin (r2 = 0.13), and between calf serum leptin and cow milk leptin (r2 = -0.06). These findings suggest that, in beef cows, maternal serum and milk leptin are related and may be involved in the regulation of their offspring’s body weight.
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