Antibacterial activity of medicinal plant extracts against some pathogenic bacteria causing skin diseases
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Abstract
This research was aimed to study antibacterial activities of 4 local medicinal plant extracts against 3 species of bacteria causing skin diseases i.e. Pseudomonas aeruginosa ATCC 27853, Staphylococcus aureus ATCC 25923 and methicillin resistant Staphylococcus aureus (MRSA). Ethanol and aqueous crude extracts of each plant were prepared to investigate the antibacterial activity by agar well diffusion assay and broth dilution method. It was found that the ethanol extract of Houttuynia cordata showed highest activity against S. aureus ATCC 25923 and MRSA with MIC of 15.63 and 7.81 mg/ml and MBC of 31.25 and 62.50 mg/ml, respectively. Moreover, the ethanolic extract of Tiliacora triandra represented highest growth inhibitory activity on MRSA and P. aeruginosa ATCC 27853, at MIC of 7.81 mg/ml and MBC of 125 mg/ml. The cytotoxicity effect of all local medicinal plant extracts on the Vero cells showed that the ethanol extract of Houttuynia cordata and Gymnema inodorum had the highest toxic effect with CD50 of 0.891 mg/ml.
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