Polyhydroxybutyrate and Its Application for Lipase Immobilization

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นาริสา บินหะยีดิง
กนกพร สังขรักษ์


Polyhydroxybutyrate (P(3HB)), is a biodegradable plastic, produced from a variety of microbial
cells. It acts as a source of carbon and energy reserving for microorganisms when bacteria are cultivated in excess carbon sources and lack of some nutrients such as nitrogen and phosphorus. P(3HB) accumulating
bacteria which can produce polyhydroxybutyrate such as Azotobacter sp. Pseudomonas sp. and Alcaligenes
eutrophus are potential strains. Currently, P(3HB) has attracted interest as it can be used as a substitute for
synthetic plastics and its features biodegradable. It is suitable for application in various fields, especially
medical. However, only few research reports had been determined on the application of polyhydroxybutyrate
for enzyme immobilization. Based on literature and the properties of P( 3HB) , it was found that
polyhydroxybutyrate has the ability to immobilize enzymes. Therefore, the basic information of
polyhydroxybutyrate, enzyme immobilization technique, enzyme immobilized with polyhydroxybutyrate and
application of immobilized lipase on polyhydroxybutyrate for biodiesel production are reviewed in this article. In addition, future research related to polyhydroxybutyrate is also indicated.


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