TRENDS, INCIDENCE AND FACTORS DETERMINING INTRAUTERINE GROWTH RESTRICTION
Keywords:
Intrauterine growth restriction, Trend, Incident rateAbstract
Objective: To determine the trend, incidence, and factors affecting fetal growth restriction among Thai women pregnants. Method: In this retrospective study, data were collected from 492 women with a singleton pregnancy who had antenal care (ANC) and delivered newborn with low birth weight in the HRH Princess Maha Chakri Sirindhorn Medical Center (MSMC) Hospital from October 1, 2014, to September 30, 2018. The individual socio-demographic, maternity records and others were reviewed. Kaplan-Meier survival analysis and Logistic regression were conducted. Results: By each fiscal year, there was no different incidence trend of fetal growth restriction. The incidence rate of fetal growth restriction was 2.4 per 100 person-weeks, the median time of GA at birth 28 weeks. The results revealed that after controlling for individual socio-demographic factors, Late ANC (OR = 2.182, CI = 1.1896 – 4.0017), GA at birth < 37 wk. (OR = 1.765 CI = 1.5679 – 1.9876) and the Ultrasound exam (OR = 0.463, CI = 0.2650 – 0.8101) were found to be significantly associated with logistic regression. Conclusion: We conclude that the late ANC and GA at the birth of pregnant women affect fetal growth restriction. Our findings suggest that the use of ultrasound examination by the second trimester may have a substantial influence on reducing intrauterine growth restriction infants.
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Murki, S., & Sharma, D. (2014). Intrauterine growth retardation - A Review Article. J Neonatal Bio, 3(3), 1-11.
ACOG. (2013 ). ACOG Practice bulletin no. 134 fetal growth restriction. Obstetrics and Gynecology, 121(5), 1122-1133.
Abdulkader, Z. M., Rahman, S. u., & Nimeri, N. (2012). The incidence of low birth weight and intrauterine growth restriction in relationship to maternal ethnicity and gestational age at birth – A PEARL study analysis from the State of Qatar. Qatar Medical Journal, 12(2).
Romo, A., Carceller, R., & Tobajas, J. (2009). Intrauterine growth retardation (IUGR): epidemiology and etiology. Pediatr Endocrinol Rev, 6(Suppl. 3), 332-336.
Mandy, G. T. (2018). Fetal growth restriction: Diagnosis. Retrieved from https://www.uptodate.com/contents/infants-with-fetal-intrauterine-growth-restriction
Sharma, D., Shastri, S., & Sharma, P. (2016). Intrauterine growth restriction: Antenatal and postnatal aspects. Clinical Medicine Insight: Pediatrics, 10, 69-83.
Haram, K., Søfteland, E., & Bukowski, R. (2013). Intrauterine growth restriction: effects of physiological fetal growth determinants on diagnosis. Obstet Gynecol Int, 1-9. doi:http://dx.doi.org/10.1155/2013/708126
Baschat, A. A. (2011). Neurodevelopment following fetal growth restriction and its relationship with antepartum parameters of placental dysfunction. Ultrasound Obstet Gynecol, 37(5), 501-514.
Figueras, F., & Gardosi, J. (2011). Intrauterine growth restriction: new concepts in antenatal surveillance, diagnosis, and management. Am J Obstet Gynecol, 204(4), 288-300.
Wang, N., Wang, X., Li, Q., Han, B., Chen, Y., Zhu, C., Lu, Y. (2017). The famine exposure in early life and metabolic syndrome in adulthood. Clinical Nutrition, 36(1), 253-259.
Malhotra, A., Allison, B. J., Castillo-Melendez, M., Jenkin, G., Polglase, G. R., & Miller, S. L. (2019). Neonatal morbidities of fetal growth restriction: Pathophysiology and impact. Frontiers in Endocrinology, 10, 1-18.
Lee, A. C. C., Kozuki, N., & Katz, J. (2017). Estimates of burden and consequences of infants born small for gestational age in low and middle income countries with INTERGROWTH-21st standard: analysis of CHERG datasets. BMJ, 358(j3677), 1-50.
World Health Organization. (2018). Screening for intrauterine growth retardation in late pregnancy. Retrieved from https://extranet.who.int/rhl/topics/preconception-pregnancy-childbirth-and-postpartum-care/antenatal-care/who-recommendation-early-ultrasound-pregnancy
Gardosi, J. (2009). Intrauterine growth restriction: new standards for assessing adverse outcome. Best Pract Res Clin Obstet Gynaecol, 23(6), 741-749.
Lausman, A., McCarthy, F. P., Walker, M., & Kingdom, J. (2012). Screening, diagnosis, and management of intrauterine growth restriction. J Obstet Gynaecol Can, 34, 17-28.
Joshi, B. R. (2017). Clinical significance of head circumferenceabdominal circumference ratio in low risk pregnancy. Journal of Institute of Medicine, 39(3), 31-35.
Borisut, P., & Kovavisarach, E. (2014). Standard intrauterine growth curve of thai neonates delivered at rajavithi hospital. J Med Assoc Thai, 97(8), 798-803.
Thongsong, T., Simaraks, S., Siivalanapa, P., Sudasna, J., Wanapirak, C., Kunavikatikul, C., & Tathayathikom, E. (1993). Study of intrauterine growth from birthweight at maharaj nakhon. J Med Assoc Thai, 76, 482-490.
Thaithumyanon, P., Bhongvej, S., & Chitinand, S. (1984). Intrauterine growth in thai population. J Pediatr Soc Thai, 23, 99-106.
Thongsong, T. (2012). Obstetric ultrasound. In T. Thongsong (Ed.), Obstetrics (pp. 651-678). Chiang Mai: Dept of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University, Thailand.
Steve, R., Beauchamp, S., Morales, C., Mirocha, J., & Esakoff, T. F. (2018). Defining fetal growth restriction: abdominal circumference as an alternative criterion. The Journal of Maternal-Fetal & Neonatal Medicine, 31(23), 3089-3094.
Strategy and planning Devision. (2560). Strategy and planning 2017 - 2021. Nonthaburi: Ministry of Public Health.
Srisa-ard, B. (2556). Research methodology. 5th ed.. Bangkok: Suweeriyasarn.
Devore, J. L., & Peck, R. (1993). Statistic: The exploration and analysis of data. New York: Duxbury Press.
Ernst, S. A., Brand, T., Reeske, A., Spallek, J., Petersen, K., & Zeeb, H. (2017). Care-related and maternal risk factors associated with the antenatal nondetection of intrauterine growth restriction: A case-control study from bremen, germany. BioMed Research International, ID 1746146, 1-10.
Tantayakom, C., & Prechapanich, J. (2008). Risk of low birth weight infants from adolescent mothers : Review case study in siriraj hospital. Thai Journal of Obstetrics and Gynaecology, 16, 103-108.
Alsadi, E., & Alawqatii, T. (2018). Disparities of clinical features and associated maternal factors among symmetrical and a symmetrical intra-uterine growth restriction (iugr) in nicu at al-yarmouk teaching hospital in Baghdad, Iraq. International Journal of Pediatrics, 6(6), 7815-7822.
Cunningham, F. G., Leveno, K. J., Bloom, S. L., Spong, C. Y., Dashe, J. S., Hoffman, B. L., Sheffield, J. S. (2014). Williams obstetrics. USA: McGraw-Hill.
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