Anti-advanced glycation end-products and α-glucosidase activities from shoot of Anacardium occidentale Linn. extract
Keywords:
Anti-advanced glycation end-product, α-glucosidase inhibitory activity, Anacardium occidentale L.Abstract
Hyperglycemia promotes the formation of protein glycation, leading to the production of advanced glycation end-products, which play a significant role in the development of complications. Therefore, the inhibition glycation is an attractive strategy in diabetes treatment. The objective of this study, methanol, dichloromethane and hexane extracts of cashew nut (Anacardium occidentale L.) shoots were evaluated for anti-glycation and α-glucosidase inhibitory activity. Investigation of protein glycation inhibitory activity of crude extracts in abovine serum albumin (BSA)/fructose system. The methanol extract showed the highest anti-advanced glycation end-product (AGEs). In addition, the methanol extract revealed highest α-glucosidase inhibitory activity against rat intestinal maltase and sucrase with an IC50 value of 0.91± 0.02 and 0.90±0.04 mg/ml, respectively, compared with acarbose (IC50 value 0.59±0.02 and 1.59±0.12 mg/ml, respectively). These results suggest that the shoots of cashew nut have a potential to be used for diabetes therapy and its complications.
References
King H, Aubert RE, Herman WH. Global burden of diabetes, 1995-2025: prevalence, numerical estimates, and projections. Diabetes Care 1998;21(9):1414-31.
Mohammad S, Ahmad J. Management of obesity in patients with type 2 diabetes mellitus in primary care. Diabetes Metab Syndr 2016;10(3):171-81.
Negre-Salvayre A, Salvayre R, Auge N, Pamplona R, Portero-Otin M. Hyperglycemia and glycation in diabetic complications. Antioxid Redox Signal 2009;11(12):3071-109.
Thornalley P. Use of aminoguanidine (pimagedine) to prevent the formation of advanced glycation endproducts. Arch Biochem Biophys 2003;419(1):31-40.
Rico R, Bulló M, Salas-Salvadó J. Nutritional composition of raw fresh cashew (Anacardium occidentale L.) kernels from different origin. Food Sci Nutr 2016;4(2):329-38.
Lopes MMdA, Miranda MRAd, Moura CFH, Enéas Filho J. Bioactive compounds and total antioxidant capacity of cashew apples (Anacardium occidentale L.) during the ripening of early dwarf cashew clones. Cienc Agrotec 2012;36(3):325-32.
Mun’im A, Katrin AA, Mahmudah KF, Mashita M. Screening of α-glucosidase inhibitory activity of some Indonesian medicinal plants. Int J Med Aromatic Plants 2013;3(2):144-50.
Suantawee T, Wesarachanon K, Anantsuphasak K, Daenphetploy T, Thien-Ngern S, Thilavech T, et al. Protein glycation inhibitory activity and antioxidant capacity of clove extract. J Food Sci Technol 2015;52(6):3843-50.
Damsud T, Grace M, Adisakwattana S, Phuwapraisirisan P. Orthosiphol A from the aerial parts of Orthosiphon aristatus is putatively responsible for hypoglycemic effect via alpha-glucosidase inhibition. Nat Prod Commun 2014;9(5):639-41.
Hossain J, Tsujiyama I, Takasugi M, Islam A, Biswas S, Aoshima H. Total phenolic content, antioxidative, anti-amylase, anti-glucosidase and antihistamine release activities of Bangladeshi fruits. J Food Sci Technol 2008;14(3):261-8.
Adisakwattana S, Sompong W, Meeprom A, Ngamukote S, Yibchok-anun S. Cinnamic acid and Its derivatives inhibit fructose-mediated protein glycation. Int J Mol Sci 2012;13(2):1778-89.
Sompong W, Cheng H, Adisakwattana S. Ferulic acid prevents methylglyoxal-induced protein glycation, DNA damage, and apoptosis in pancreatic beta-cells. J Physiol Biochem 2017;73(1):121-31.
Suantawee T, Cheng H, Adisakwattana S. Protective effect of cyanidin against glucoseand methylglyoxal-induced protein glycation and oxidative DNA damage. Int J Biol Macromol 2016;93(PtA):814-21.
Thilavech T, Ngamukote S, Belobrajdic D, Abeywardena M, Adisakwattana S. Cyanidin-3-rutinoside attenuates methylglyoxal-induced protein glycation and DNA damage via carbonyl trapping ability and scavenging reactive oxygen species. BMC Complement Altern Med 2016;16:138.
Konan A, Bacchi M. Antiulcerogenic effect and acute toxicity of a hydroethnolic extract from the chashew (Anacardium occidentale L.) leaves. J Ethnopharmacol 2007;112(2):237-42.
Arya R, Babu V, Lllyas M, Nassim T. Phytochemical examination of the leaves of Anacardium occidentale. J Indian Chem Soc 1989;66:67-8.
Yin Z, Zhang W, Feng F, Zhang Y, Kang W. a-Glucosidase inhibitors isolated from medicinal plants. Food Sci Human Wellness 2014;(3-4):136-74.
Chu Y, Wu S, Hsieh J. Isolation and characterization of a-glucosidase inhibitory constituents from Rhodiola crenulata. Food Res Int 2014;(57):8-14.
Moronkola OD, Kasali AA, Ekundayo O. Composition of the limonene dominated leaf essential oil of Nigerian Anacardium occidentale. J Essent Oil Res 2011;19(4):351-3.
Zhao J, Zhou XW, Chen XB, Wang QX. α-Glucosidase inhibitory constituents from Toona sinensis. Chem Nat Compd 2009;45(2):244-6.
Ojewole JA. Laboratory evaluation of the hypoglycemic effect of Anacardium occidentale Linn. (Anacardiaceae) stem-bark extracts in rats. Methods Find Exp Clin Pharmacol 2003;25(3):199-204.
Jaiswal YS, Tatke PA, Gabhe SY, Vaidya AB. Antidiabetic activity of extracts of Anacardium occidentale Linn. leaves on n-streptozotocin diabetic rats. J Tradit Complement Med 2017;7(4):421-7.
Downloads
Published
How to Cite
Issue
Section
License
บทความทุกบทความที่ได้รับการตีพิมพ์ถือเป็นลิขสิทธิ์ของ คณะวิทยาศาสตร์แฟละเทคโนโลยี มหาวิทยาลัยหัวเฉียวเฉลิมพระเกียรติ
