Histological study of coronary artery in Thai cadavers
Keywords:
Coronary artery, Histology, Cadaver, Arterial wall, Tunica intimaAbstract
Cardiovascular disease is the leading cause of death for people worldwide and found that the incidence of atherosclerosis in the coronary arteries is sharply increasing in the elderly. The objectives of this research were to study the histology and arterial wall thickness of the left and right coronary artery of 20 Thai cadavers aged 52–101 years with Hematoxylin and eosin staining and Verhoeff-Van Gieson. The thickness of the tunica intima of the right coronary artery was significantly thicker than the tunica media (p < 0.05), and large accumulations of foam cells were found in the wall of left and right coronary arteries. Other plaques included the lipid core, fibrous cap, calcifications, and cholesterol cleft, and abnormalities of the internal and external elastic lamina were observed, there were straight, reduplication, stretch, and fraying. It was shown that people aged over 50 will have histological changes to the arterial wall. This may lead to the development of atherosclerosis. The results of this research will be the basis of information that can be applied in risk assessment and surveillance of coronary artery disease.
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